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Arsene Wenger will rest several of his first-team stars when Arsenal play Galatasaray in their final Champions League group game on Tuesday.
The Gunners have already qualified for the last-16 following last month's victory against Borussia Dortmund and Wenger is aware that he can ill-afford many more injuries to his squad.
He has already confirmed that Alexis Sanchez and Laurent Koscielny will not travel to Istanbul and could field an inexperienced line-up against the Turkish side.
Arsenal could still finish top of Group D should they win in Istanbul and Borussia Dortmund lose at home to Anderlecht.
"We play many, many, many games and some players are really on the fringe of getting serious injury risk so we will assess the situation," said Wenger.
"But we will go with a strong team because we want to win the game. We have, out of this campaign, played seven Champions League games and won four. I would like to win five.
"A few players will not travel because there is not a lot at stake and we have given a lot in the last two weeks."
Sanchez will be given a few days off while Koscielny will not be risked as the Frenchman continues to recover from an Achilles problem.
The central defender did not feature in the 3-2 defeat at Stoke City having recently played two games in four days following an eight-week absence.
Theo Walcott's groin injury means he will not play in Turkey, while Santi Cazorla and Calum Chambers look set to be rested after looking jaded against the Potters.
Hector Bellerin, Isaac Hayden, Joel Campbell and Lukas Podolski are all tipped to feature in Istanbul.
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